TRAT1 monoclonal antibody, clone TRIM-04 (PE)
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant TRAT1.
Immunogen
Recombinant protein corresponding to partial human TRAT1.
Host
Mouse
Theoretical MW (kDa)
30
Reactivity
Human
Specificity
This antibody reacts with T cell receptor-interacting molecule (TRIM), a 30 KDa adaptor protein expressed by T cells.
Form
Liquid
Conjugation
PE
Concentration
0.1 mg/mL
Isotype
IgG2a
Recommend Usage
Flow Cytometry (1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
Flow Cytometry
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Gene Info — TRAT1
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Interactome
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Publication Reference
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Transmembrane adaptor molecules: a new category of lymphoid-cell markers.
Tedoldi S, Paterson JC, Hansmann ML, Natkunam Y, Rudiger T, Angelisova P, Du MQ, Roberton H, Roncador G, Sanchez L, Pozzobon M, Masir N, Barry R, Pileri S, Mason DY, Marafioti T, Horejsi V.
Blood 2005 Sep; 107(1):213.
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Right time, right place: the organization of membrane proximal signaling.
Simeoni L, Smida M, Posevitz V, Schraven B, Lindquist JA.
Seminars in Immunology 2005 Feb; 17(1):35.
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The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.
Kirchgessner H, Dietrich J, Scherer J, Isomaki P, Korinek V, Hilgert I, Bruyns E, Leo A, Cope AP, Schraven B.
The Journal of Experimental Medicine 2001 Jun; 193(11):1269.
Application:IF, WB-Ce, WB-Tr, Human, Peripheral blood T, Jurkat T cells.
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Transmembrane adaptor molecules: a new category of lymphoid-cell markers.
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