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Last updated: 2017/11/19
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ACRV1 monoclonal antibody, clone Hs-14 (FITC)

  • Catalog # : MAB4490
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ACRV1.
  • Immunogen:
  • Native purified human ACRV1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 220
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody reacts with a 220 KDa testis-specific human intra-acrosomal protein associated with the membranes of the acrosomal vesicle.
  • Form:
  • Liquid
  • Conjugation:
  • FITC
  • Isotype:
  • IgM
  • Recommend Usage:
  • Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 56
  • Gene Name:
  • ACRV1
  • Gene Alias:
  • D11S4365,SP-10,SPACA2
  • Gene Description:
  • acrosomal vesicle protein 1
  • Gene Summary:
  • This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. [provided by RefSeq
  • Other Designations:
  • sperm protein 10
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