Mouse monoclonal antibody raised against native SELP.
Native purified SELP from human platelets.
Theoretical MW (kDa):
This antibody recognizes CD62P (P-selectin), a 140 KDa single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes; it is relocated to the plasma membrane upon activation.
Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user.
In PBS (0.2% BSA, 0.09% sodium azide)
Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq
OTTHUMP00000032609,antigen CD62,granulocyte membrane protein,leukocyte-endothelial cell adhesion molecule 3,platelet alpha-granule membrane protein,selectin P,selectin P (granule membrane protein 140kD, antigen CD62)