Mouse monoclonal antibody raised against recombinant IL16.
Recombinant protein corresponding to human IL16.
Reacts with human IL-16. Does not cross react with human serum albumin, Bovine serum albumin and other human cytokines or growth factors tested such as IL-1 beta, IL-8, IL-7, MCAF, TGF-beta 1, EGF, bFGF, GM-CSF, M-CSF and TNF-alpha.
Western Blot (2.5 ug/mL will allow visualization of 1ug/lane of human IL-16) The optimal working dilution should be determined by the end user.
Lyophilized from 10 mM PBS, pH 7.2
Store at 4°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq