CGB monoclonal antibody, clone 057-10043
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Specification
Product Description
Mouse monoclonal antibody raised against native CGB.
Immunogen
Native purified CGB from human pregnancy urine.
Host
Mouse
Reactivity
Human
Specificity
When tested by ELISA, this antibody is specific to intact-hCG and its beta subunit. Does not cross react with hCG alpha subunit.
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 10 mM sodium phosphate buffer, pH 7.4 (150 mM NaCl, 0.05% sodium azide)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
Sandwich ELISA
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Gene Info — CGB
Entrez GeneID
1082Gene Name
CGB
Gene Alias
CGB3, hCGB
Gene Description
chorionic gonadotropin, beta polypeptide
Omim ID
118860Gene Ontology
HyperlinkGene Summary
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq
Other Designations
chorionic gonadotropin beta 3 subunit|chorionic gonadotropin beta chain|chorionic gonadotropin beta subunit
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Interactome
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Disease
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Publication Reference
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Quantitative, wide-range, 5-minute point-of-care immunoassay for total human chorionic gonadotropin in whole blood.
von Lode P, Rainaho J, Pettersson K.
Clinical Chemistry 2004 Apr; 50(6):1026.
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Quantitative, wide-range, 5-minute point-of-care immunoassay for total human chorionic gonadotropin in whole blood.
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