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Last updated: 2016/12/4
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B3GAT1 monoclonal antibody, clone VC1.1

  • Catalog # : MAB4196
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native B3GAT1.
  • Immunogen:
  • Native purified B3GAT1 from cat unfixed cortical homogenate area 17.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes a (110KDa) carbohydrate molecule on myeloid cells. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
  • Form:
  • Liquid
  • Isotype:
  • IgM
  • Recommend Usage:
  • Flow Cytometry (1ug stain 1.0x106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.2 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Gene Information
  • Gene Name:
  • B3GAT1
  • Gene Alias:
  • CD57,GLCATP,GlcAT-P,GlcUAT-P,HNK-1,HNK1,LEU7,NK-1
  • Gene Description:
  • beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
  • Gene Summary:
  • The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq
  • Other Designations:
  • CD57 antigen,LEU7 antigen,UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase,beta-1,3-glucuronyltransferase 1,galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,glucuronosyltransferase P
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