Anti-Mouse CD54 (ICAM-1) recognizes the 95KDa cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 and Mac-1.1, 2, 3. Anti-CD54 blocks the binding of LFA-1 to ICAM-1. The CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Flow Cytometry (1ug stain 1.0x106 cells) The optimal working dilution should be determined by the end user.
In 10 mM PBS, pH 7.2 (1% BSA, 0.09% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.