Recognizes the c1 epitope, a conformational epitope which is only detectable when the alpha and beta subunits of FSH are associated (intact FSH). No cross-reaction is detected in RIA with human FSH beta or any other human glycoprotein hormone or subunit thereof. Two-site sandwich ELISA revealed recognition of a conformational epitope on intact human FSH which is located near the alpha 1, alpha 2 and alpha 4 epitopes.
The optimal working dilution should be determined by the end user.
In Hanks balanced salt solution (0.09% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq