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Last updated: 2016/12/4
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FGA/FGB/FGG monoclonal antibody, clone FgA

  • Catalog # : MAB4090
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against FGA/FGB/FGG.
  • Immunogen:
  • Human fibrinogen.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Fibrinogen.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 10 mM sodium phosphate buffer, 150 mM NaCl, pH 7.4 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • FGA/FGB/FGG monoclonal antibody, clone FgA (Cat # MAB4090) strongly detects multiple cleavage products of human Fibrinogen only under reduced conditions (Lan 1).
    Under non-reduced conditions (Lane 2) it detects a major band above 209 kDa and some faint bands around 45 kDa.
  • ELISA
  • Enzyme Immunoassay
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • ELISA
  • Enzyme Immunoassay
  • Gene Information
  • Entrez GeneID:
  • 2243
  • Gene Name:
  • FGA
  • Gene Alias:
  • Fib2,MGC119422,MGC119423,MGC119425
  • Gene Description:
  • fibrinogen alpha chain
  • Gene Summary:
  • The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq
  • Other Designations:
  • fibrinogen, A alpha polypeptide,fibrinogen, alpha chain, isoform alpha preproprotein,fibrinogen, alpha polypeptide
  • Gene Information
  • Entrez GeneID:
  • 2244
  • Gene Name:
  • FGB
  • Gene Alias:
  • MGC104327,MGC120405
  • Gene Description:
  • fibrinogen beta chain
  • Gene Summary:
  • The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq
  • Other Designations:
  • fibrinogen, B beta polypeptide,fibrinogen, beta chain
  • Gene Information
  • Entrez GeneID:
  • 2266
  • Gene Name:
  • FGG
  • Gene Alias:
  • -
  • Gene Description:
  • fibrinogen gamma chain
  • Gene Summary:
  • The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • fibrinogen, gamma chain,fibrinogen, gamma polypeptide
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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