CALB2 monoclonal antibody, clone 6B3
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant CALB2.
Immunogen
Recombinant protein corresponding to human CALB2.
Host
Mouse
Reactivity
Human, Rat
Specificity
This antibody reacts with Calretinin 22 KDa, no cross-reaction with Calbindin and Calmodulin.
Form
Liquid
Isotype
IgG
Recommend Usage
Western Blot (1:40-1:50)
Immunohistochemistry (1:40-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In phosphate buffer, pH 7.3 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
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Gene Info — CALB2
Entrez GeneID
794Gene Name
CALB2
Gene Alias
CAL2
Gene Description
calbindin 2
Omim ID
114051Gene Ontology
HyperlinkGene Summary
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Three alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq
Other Designations
calbindin 2, (29kD, calretinin)|calbindin D29K|calretinin
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Interactome
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Disease
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Publication Reference
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The Role of Parvalbumin Containing Interneurons in the Regulation of Spontaneous Synchronous Activity of Brain Neurons in Culture.
Zinchenko VP, Turovskaya MV, Teplov IY, Berezhnov AV, Turovsky EA.
Cell Biophysics 2015 Nov; 61(1):85.
Application:ICC, IF, Rat, Rat brain neuron.
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Monoclonal antibodies recognizing epitopes of calretinins: dependence on Ca2+-binding status and differences in antigen accessibility in colon cancer cells.
Zimmermann L, Schwaller B.
Cell Calcium 2002 Jan; 31(1):13.
Application:IF, WB-Re, Chicken, Fish, Human, Monkey, Mouse, Pig, Rat, Recombinant protein, WiDr cells.
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Calretinin: a novel immunocytochemical marker for mesothelioma.
C Doglioni, A P Dei Tos, L Laurino, P Iuzzolino, C Chiarelli, M R Celio, G Viale.
The American Journal of Surgical Pathology 1996 Sep; 20(9):1037.
Application:IHC-P, Human, Human cerebral cortex, Human malignant mesotheliomas.
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The calcium binding protein calretinin is a selective marker for malignant pleural mesotheliomas of the epithelial type.
Gotzos V, Vogt P, Celio MR.
Pathology, Research and Practice 1996 Feb; 192(2):137.
Application:IHC-P, Human, Human adenocarcinomas, Human pleural mesotheliomas.
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The Role of Parvalbumin Containing Interneurons in the Regulation of Spontaneous Synchronous Activity of Brain Neurons in Culture.
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