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COL17A1 monoclonal antibody, clone B1052M

  • Catalog # : MAB3963
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant COL17A1.
  • Immunogen:
  • Recombinant GST fusion protein corresponding to amino acids 1-490 of human COL17A1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • human type XVII collagen/BP180 (amino acids 1-490)
  • Form:
  • Lyophilized
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • ELISA(1:1000)
    Western blot(1:100)
    Immunohistochemistry(Frozen sections)(1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 50 mM Tris, pH 7.4
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 1308
  • Gene Name:
  • COL17A1
  • Gene Alias:
  • BA16H23.2,BP180,BPAG2,FLJ60881,KIAA0204,LAD-1
  • Gene Description:
  • collagen, type XVII, alpha 1
  • Gene Summary:
  • This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020422,alpha 1 type XVII collagen,bA16H23.2 (collagen, type XVII, alpha 1 (BP180)),bullous pemphigoid antigen 2 (180kD),collagen XVII, alpha-1 polypeptide
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