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Last updated: 2016/11/27
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CDH15 monoclonal antibody, clone 21G4

  • Catalog # : MAB3922
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CDH15.
  • Immunogen:
  • Recombinant protein corresponding to extracellular region of human CDH15.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Cadherins are a family of transmembrane glycoproteins that play a key role in Calcium dependent cell-cell adhesion. Several members of the cadherin family have been identified so far, including E- (epithelial), P- (placental), N- (neuronal) and M- (muscle) cadherin. M-Cadherin is expressed in myoblasts and might be involved in skeletal muscle cell differentiation. Does not cross-react with mouse.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (0.05 ug/mL)
    Western Blot (1 ug/mL for AP/BCIP/NBT (MTT) detection 0.5 ug/mL for HRP/ECL detection)
    Immunofluorescence (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 2x PBS (PEG, sucrose, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of whole cell lysates with CDH15 monoclonal antibody, clone 21G4 (Cat # MAB3922) for 1 hour at RT and developed by ECL.
    Lane 1 : COS-7.
    Lane 2 : Human CDH15 overexpressed in COS-7 cells.
  • Immunofluorescence
  • Enzyme Immunoassay
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunofluorescence
  • Enzyme Immunoassay
  • Gene Information
  • Entrez GeneID:
  • 1013
  • Gene Name:
  • CDH15
  • Gene Alias:
  • CDH14,CDH3,CDHM,MCAD
  • Gene Description:
  • cadherin 15, type 1, M-cadherin (myotubule)
  • Gene Summary:
  • This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq
  • Other Designations:
  • M-cadherin,cadherin 15,cadherin 15, M-cadherin (myotubule),cadherin-14,cadherin-3,muscle-cadherin,myotubule-cadherin
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