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Last updated: 2017/3/26
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HLA-G monoclonal antibody, clone 4H84

  • Catalog # : MAB3858
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against HLA-G .
  • Immunogen:
  • Amino acid 61-83 of human HLA-G.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 39
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes HLA-G molecule (39 KDa). HLA-G belongs to the MHC ClassI molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of HLA-G from HLA-G1 transfectants (LCL-HLA-G1) by HLA-G monoclonal antibody, clone 4H84 (Cat # MAB3858) and protein G.
    HLA-G was detected by HLA-G monoclonal antibody, clone 4H84 (Cat # MAB3858) and goat anti-mouse-HRP conjugate in cell lysate (Lane 1) and in the immunoprecipitate (Lane 2).
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3135
  • Gene Name:
  • HLA-G
  • Gene Alias:
  • MHC-G
  • Gene Description:
  • major histocompatibility complex, class I, G
  • Gene Summary:
  • HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq
  • Other Designations:
  • HLA class I molecule,HLA-G histocompatibility antigen, class I, G,MHC class I antigen,OTTHUMP00000039485,b2 microglobulin
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