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Last updated: 2017/1/15
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CD47 monoclonal antibody, clone MEM-122

  • Catalog # : MAB3839
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD47.
  • Immunogen:
  • Native purified CD47 from African Green Monkey COS-7 cells.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 50-55
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with CD47 (Integrin Associated Protein), a 50-55 KDa membrane adhesion molecule (thrombospondin receptor; immunoglobulin supergenefamily) expressed on leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines.
  • Form:
  • Liquid
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Flow Cytometry
  • Flow Cytometry
  • Surface staining of lysed and washed porcine peripheral blood with CD47 monoclonal antibody, clone MEM-122 (Cat # MAB3839) (detection by anti-mouse IgM FITC).
    Panel A - porcine PBMC stained with Isotype mouse IgM control.
    Panel B, C, D - porcine PBMC sample stained with CD47 monoclonal antibody, clone MEM-122 (Cat # MAB3839). Cells in the granulocyte gate were used for analysis.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 961
  • Gene Name:
  • CD47
  • Gene Alias:
  • IAP,MER6,OA3
  • Gene Description:
  • CD47 molecule
  • Gene Summary:
  • This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD47 antigen,CD47 antigen (Rh-related antigen, integrin-associated signal transducer),CD47 glycoprotein,Rh-related antigen,antigen identified by monoclonal antibody 1D8,antigenic surface determinant protein OA3,integrin associated protein,integrin-associa
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