Mouse monoclonal antibody raised against native CD47.
Native purified CD47 from African Green Monkey COS-7 cells.
Theoretical MW (kDa):
This antibody reacts with CD47 (Integrin Associated Protein), a 50-55 KDa membrane adhesion molecule (thrombospondin receptor; immunoglobulin supergenefamily) expressed on leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines.
The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (0.09% sodium azide)
Store at 4°C. Do not freeze.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Surface staining of lysed and washed porcine peripheral blood with CD47 monoclonal antibody, clone MEM-122 (Cat # MAB3839) (detection by anti-mouse IgM FITC). Panel A - porcine PBMC stained with Isotype mouse IgM control. Panel B, C, D - porcine PBMC sample stained with CD47 monoclonal antibody, clone MEM-122 (Cat # MAB3839). Cells in the granulocyte gate were used for analysis.
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
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