LRP1 monoclonal antibody, clone MA8B8
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Specification
Product Description
Mouse monoclonal antibody raised against LRP1.
Immunogen
Human 85 kDa low density LRP1.
Host
Mouse
Reactivity
Human, Rabbit
Specificity
This purified mouse monoclonal antibody cross reacts with human and rabbit and is specific to the 85 KDa light chain of LDL Receptor-Related Protein (LRP).
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1-5 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM NaCl, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — LRP1
Entrez GeneID
4035Gene Name
LRP1
Gene Alias
A2MR, APOER, APR, CD91, FLJ16451, IGFBP3R, LRP, MGC88725, TGFBR5
Gene Description
low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
Omim ID
107770Gene Ontology
HyperlinkOther Designations
TbetaR-V/LRP-1/IGFBP-3 receptor|alpha-2-macroglobulin receptor|low density lipoprotein-related protein 1|type V tgf-beta receptor
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Interactome
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Disease
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Publication Reference
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Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
Coukos G, Gåfvels ME, Wisel S, Ruelaz EA, Strickland DK, Strauss JF 3rd, Coutifaris C.
The American Journal of Pathology 1994 Feb; 144(2):383.
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Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions.
Rebeck GW, Reiter JS, Strickland DK, Hyman BT.
Neuron 1993 Oct; 11(4):575.
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Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.
Strickland DK, Ashcom JD, Williams S, Burgess WH, Migliorini M, Argraves WS.
The Journal of Biological Chemistry 1990 Oct; 265(29):17401.
Application:ELISA, IP, WB-Ce, WB-Re, Human, Human gingival fibroblasts, Purified proteins.
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Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
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