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Last updated: 2016/11/27
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SERPINE1 monoclonal antibody, clone 33H1F7

  • Catalog # : MAB3801
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant SERPINE1.
  • Immunogen:
  • Recombinant protein corresponding to human SERPINE1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This mouse monoclonal antibody is specific to plasminogen activator inhibitor-1 (PAI-1) and exhibits inhibitory characteristics. This antibody binds to the F-Helix of PAI-1. This PAI-1 complex acts as a substrate for its target proteinases tPA and uPA.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 100 mM sodium phosphate buffer, 100 mM NaCl, pH 7.4
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • ELISA
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5054
  • Gene Name:
  • SERPINE1
  • Gene Alias:
  • PAI,PAI-1,PAI1,PLANH1
  • Gene Description:
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Gene Summary:
  • This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • plasminogen activator inhibitor, type I,plasminogen activator inhibitor-1,serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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