SPARC monoclonal antibody, clone A3A8
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Specification
Product Description
Mouse monoclonal antibody raised against SPARC.
Immunogen
N-terminus half of human SPARC.
Host
Mouse
Reactivity
Bovine, Human, Rat
Specificity
Reacts with bone and platelet osteonectin. human platelet osteonectin. human, bovine and rat bone osteonectin.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
Radioimmunoassay
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Gene Info — SPARC
Entrez GeneID
6678Gene Name
SPARC
Gene Alias
ON
Gene Description
secreted protein, acidic, cysteine-rich (osteonectin)
Omim ID
182120Gene Ontology
HyperlinkGene Summary
Secreted protein acidic and rich in cysteine/osteonectin/BM40, or SPARC, is a matrix-associated protein that elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix (ECM) (Bradshaw et al., 2003 [PubMed 12721366]).[supplied by OMIM
Other Designations
cysteine-rich protein|osteonectin|secreted protein, acidic, cysteine-rich
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Interactome
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Disease
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