LEP monoclonal antibody, clone A130D 1H6 2B9 BE8
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant LEP.
Immunogen
Recombinant protein corresponding to human LEP.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes natural and recombinant human LEP.
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at 4°C.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — LEP
Entrez GeneID
3952Gene Name
LEP
Gene Alias
FLJ94114, OB, OBS
Gene Description
leptin
Omim ID
164160Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq
Other Designations
leptin (murine obesity homolog)|leptin (obesity homolog, mouse)|obese, mouse, homolog of|obesity factor
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Interactome
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Pathway
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Disease
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