GH1 monoclonal antibody, clone 4/2G7 1C3
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant GH1.
Immunogen
Recombinant protein corresponding to human GH1.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes natural and recombinant human GH1.
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Radioimmunoassay
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Gene Info — GH1
Entrez GeneID
2688Gene Name
GH1
Gene Alias
GH, GH-N, GHN, hGH-N
Gene Description
growth hormone 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq
Other Designations
pituitary growth hormone
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Interactome
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Pathway
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Disease
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