KRT10 monoclonal antibody, clone VIK-10
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Specification
Product Description
Mouse monoclonal antibody raised against native KRT10.
Immunogen
Native purified human KRT10.
Host
Mouse
Theoretical MW (kDa)
56.5
Reactivity
Human
Specificity
This antibody reacts with KRT10 (Cytokeratin 10; 56.5 KDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Form
Liquid
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry staining of human skin basaliom (paraffin-embedded sections) with KRT10 monoclonal antibody, clone VIK-10 (Cat # MAB3663).Immunocytochemistry
Immunoprecipitation
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Gene Info — KRT10
Entrez GeneID
3858Gene Name
KRT10
Gene Alias
CK10, K10, KPP
Gene Description
keratin 10
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq
Other Designations
cytokeratin 10
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Interactome
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Publication Reference
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Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells.
Ivanyi D, Minke JM, Hageman C, Groeneveld E, van Doornewaard G.
Am J Vet Res 1992 Mar; 53(3):304.
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Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells.
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