Product Browser

Last updated: 2016/12/4
  • Related Product Showcase
  • By Biomarker

  • By Application

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

DEFA1/DEFA3 monoclonal antibody, clone DEF-3

  • Catalog # : MAB3586
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native DEFA1/DEFA3.
  • Immunogen:
  • Native purified human DEFA1/DEFA3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human Neutrophil Peptides (HNP1-3) syn. alpha-Defensins 1-3, reactivity with HNP-4 not tested.
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from purified antibody in PBS (BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 1667
  • Gene Name:
  • DEFA1
  • Gene Alias:
  • DEF1,DEFA2,HNP-1,HP-1,MGC138393,MRS
  • Gene Description:
  • defensin, alpha 1
  • Gene Summary:
  • Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000196017,defensin, alpha 1, myeloid-related sequence,defensin, alpha 2,myeloid-related sequence
  • Gene Information
  • Entrez GeneID:
  • 1668
  • Gene Name:
  • DEFA3
  • Gene Alias:
  • DEF3,HNP-3,HNP3,HP-3
  • Gene Description:
  • defensin, alpha 3, neutrophil-specific
  • Gene Summary:
  • Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 1 by only one amino acid. [provided by RefSeq
  • Other Designations:
  • defensin 3, neutrophil-specific,defensin, alpha 3,neutrophil peptide 3
  • RSS
  • YouTube
  • Linkedin
  • Facebook