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Last updated: 2016/11/27
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TSHR monoclonal antibody, clone 4C1/E1/G8

  • Catalog # : MAB3576
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TSHR.
  • Immunogen:
  • Recombinant protein corresponding to the extracellular region of human TSHR.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • human thyrotrophin receptor (aa sequence 211-414).
  • Form:
  • Liquid
  • Concentration:
  • 50 ug/mL
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunohistochemistry (1:10-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In phosphate buffer, pH 7.3 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 7253
  • Gene Name:
  • TSHR
  • Gene Alias:
  • CHNG1,LGR3,MGC75129,hTSHR-I
  • Gene Description:
  • thyroid stimulating hormone receptor
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • seven transmembrane helix receptor,thyroid stimulating hormone receptor, isoform 2,thyrotropin receptor,thyrotropin receptor-I, hTSHR-I
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