MKI67 monoclonal antibody, clone MIB-1
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Specification
Product Description
Mouse monoclonal antibody raised against MKI67.
Immunogen
Native purified MKI67 from human nuclear Ki-67 antigen.
Host
Mouse
Reactivity
Human
Specificity
This antibody reacts with MKI67 nuclear protein.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In phosphate buffer, pH 7.3 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — MKI67
Entrez GeneID
4288Protein Accession#
P46013Gene Name
MKI67
Gene Alias
KIA, Ki-67
Gene Description
antigen identified by monoclonal antibody Ki-67
Omim ID
176741Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq
Other Designations
OTTHUMP00000020739|proliferation-related Ki-67 antigen
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Interactome
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Disease
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Publication Reference
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Immunohistological detection of tumour growth fraction (Ki-67 antigen) in formalin-fixed and routinely processed tissues.
Gerdes J, Becker MH, Key G, Cattoretti G.
The Journal of Pathology 1992 Sep; 168(1):85.
Application:IHC-Fr, IHC-P, WB-Ce, WB-Ti, Human, Lung tumors, Tonsils.
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Prognostic relevance of tumour-cell growth fraction in malignant non-Hodgkin's lymphomas.
Gerdes J, Stein H, Pileri S, Rivano MT, Gobbi M, Ralfkiaer E, Nielsen KM, Pallesen G, Bartels H, Palestro G, et al..
Lancet (London, England) 1987 Aug; 2(8556):448.
Application:IHC, Human, Human malignant non-Hodgkin's lymphomas.
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Immunohistological detection of tumour growth fraction (Ki-67 antigen) in formalin-fixed and routinely processed tissues.
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