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Last updated: 2016/11/27
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FLG monoclonal antibody, clone FLG01

  • Catalog # : MAB3538
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant FLG.
  • Immunogen:
  • Recombinant protein corresponding to human FLG.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 38, 400
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human filaggrin 38 KDa and pro-filaggrin (~ 400 KDa).
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 2312
  • Gene Name:
  • FLG
  • Gene Alias:
  • ATOD2
  • Gene Description:
  • filaggrin
  • Gene Summary:
  • Profilaggrin is a major protein component of the keratohyalin granules of mammalian epidermis. It is initially expressed as a large polyprotein precursor which is subsequently proteolytically processed into individual functional filaggrin molecules. The filaggrins show wide species variations and their aberrant expression has been implicated in a number of keratinizing disorders (Baden et al., 1974 [PubMed 4132224]; Holbrook et al., 1982 [PubMed 6174530]; Sybert et al., 1985 [PubMed 2579164]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000014057,epidermal filaggrin
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