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Last updated: 2016/11/27
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CD68 monoclonal antibody, clone PG-M1

  • Catalog # : MAB3514
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD68.
  • Immunogen:
  • Native purified CD68 from Gaucher cells.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 110
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with CD68 transmembrane glycoprotein MW 110 KDa, localised in macrophages.
  • Form:
  • Liquid
  • Isotype:
  • IgG3, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In phosphate buffer, pH 7.3 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 968
  • Gene Name:
  • CD68
  • Gene Alias:
  • DKFZp686M18236,GP110,SCARD1
  • Gene Description:
  • CD68 molecule
  • Gene Summary:
  • This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • CD68 antigen,OTTHUMP00000135285,macrophage antigen CD68,macrosialin,scavenger receptor class D, member 1
  • Gene Pathway
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