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Last updated: 2017/10/15
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ABCC3 monoclonal antibody, clone DTX1

  • Catalog # : MAB3489
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ABCC3.
  • Immunogen:
  • Recombinant protein corresponding to cytoplasmic region between transmembrane regions 11 and 12 of human ABCC3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes human multidrug resistance-associated protein 3.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from tissue culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with distilled water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 8714
  • Gene Name:
  • ABCC3
  • Gene Alias:
  • ABC31,EST90757,MLP2,MOAT-D,MRP3,cMOAT2
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, sub-family C, member 3,canicular multispecific organic anion transporter,multidrug resistance associated protein
  • Gene Pathway
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