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Last updated: 2017/8/20
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ABCC6 monoclonal antibody, clone M6II-31

  • Catalog # : MAB3476
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against recombinant ABCC6.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 764-964 of human ABCC6.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Specificity:
  • M6II-31 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MPR4 and MRP5 gene products.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunocytochemistry (1:20-50)
    Western Blot (1:20-50)
    Immunohistochemistry (Frozen sections) (1:20-50)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 368
  • Gene Name:
  • ABCC6
  • Gene Alias:
  • ABC34,ARA,EST349056,MLP1,MOATE,MRP6,PXE,PXE1
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 6
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, sub-family C, member 6,anthracycline resistance-associated
  • Gene Pathway
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