Rat monoclonal antibody raised against recombinant ABCC6.
Recombinant protein corresponding to amino acids 764-964 of human ABCC6.
M6II-31 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MPR4 and MRP5 gene products.
Immunocytochemistry (1:20-50) Western Blot (1:20-50) Immunohistochemistry (Frozen sections) (1:20-50) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20) The optimal working dilution should be determined by the end user.
In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
ATP-binding cassette, sub-family C, member 6,anthracycline resistance-associated