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Last updated: 2017/11/19
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TNFRSF10A monoclonal antibody, clone HS101

  • Catalog # : MAB3473
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant TNFRSF10A.
  • Immunogen:
  • Recombinant protein corresponding to human TNFRSF10A.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3, or -R4.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunocytochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric detection of endogenous TNFRSF10A. BJAB cells (1 X 106) were stained with TNFRSF10A monoclonal antibody, clone HS101 (Cat # MAB3473) (Black histogram) or with an unspecified mouse IgG1 antibody as a control (white histogram).
  • Flow Cytometry
  • Flow Cytometry
  • Receptor specificity of the TNFRSF10A monoclonal antibody, clone HS101 (Cat # MAB3473). CV1/EBNA cells were transfected either with the empty expression vector pCDNA3 (vector control) or pCDNA3 encoding TNFRSF10A to TNFRSF10D. Two days after transfection, 1 X 106 cells were stained with TNFRSF10A monoclonal antibody, clone HS101 (Cat # MAB3473).
  • Application Image
  • Immunocytochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 8797
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 10a
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq
  • Other Designations:
  • TNF-related apoptosis inducing ligand receptor 1,cytotoxic TRAIL receptor,death receptor 4
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