GSTP1 monoclonal antibody, clone Usal-hGST-Pi-McAb-1
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against recombinant GSTP1.
Immunogen
Recombinant protein corresponding to human GSTP1.
Host
Mouse
Reactivity
Human, Leishmania, Rat
Specificity
Recognizes human, rat and leishmania GST-Pi. Does not cross-react with human or rat alpha GST.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (Frozen sections) (1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 100 nM sodium azide
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Panel A : Polyacrylamide gel electrophoresis (SDS-PAGE) and Coomassie brilliant blue staining of molecular weight standard (MW), pure GSTP1 protein and liver homogenate (5 ug protein) from normal rat liver (Control) or from liver tissue containing neoplastic lesions at different time points during hepatocarcinogenesis.
Panel B : Western blot using GSTP1 monoclonal antibody, clone Usal-hGST-Pi-McAb-1 (Cat # MAB3452).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of rat livers at 12, 20 or 32 weeks after initiation of liver carcinogensis. GSTP1-postive tissue was stained with GSTP1 monoclonal antibody, clone Usal-hGST-Pi-McAb-1 (Cat # MAB3452) in a 30 um thick rat liver slice. Original magnification 4X.Immunohistochemistry (Frozen sections)
-
Gene Info — GSTP1
Entrez GeneID
2950Gene Name
GSTP1
Gene Alias
DFN7, FAEES3, GST3, PI
Gene Description
glutathione S-transferase pi 1
Omim ID
134660Gene Ontology
HyperlinkGene Summary
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq
Other Designations
OTTHUMP00000174659|deafness, X-linked 7|fatty acid ethyl ester synthase III|glutathione transferase
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com