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Last updated: 2017/9/17
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XRCC1 monoclonal antibody, clone 33-2-5

  • Catalog # : MAB3419
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant XRCC1.
  • Immunogen:
  • Recombinant protein corresponding to human XRCC1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This clone recognizes a protein of approximately 85 KDa identified as the XRCC1.
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed, paraffin embedded human testis stained with XRCC1 monoclonal antibody, clone 33-2-5 (Cat # MAB3419)
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation (Native verified) of LS174T cell line of XRCC1 monoclonal antibody, clone 33-2-5 (Cat # MAB3419). Use Protein A. Use antibody at 2 ug/mg protein lysate.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 7515
  • Gene Name:
  • XRCC1
  • Gene Alias:
  • RCC
  • Gene Description:
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • Gene Summary:
  • The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
  • Other Designations:
  • DNA repair protein XRCC1,X-ray repair cross complementing protein 1,X-ray-repair, complementing defective, repair in Chinese hamster
  • Gene Pathway
  • Related Disease
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