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Last updated: 2016/10/23
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TNFRSF11B monoclonal antibody, clone Bony-1

  • Catalog # : MAB3414
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against partial recombinant TNFRSF11B.
  • Immunogen:
  • Recombinant Fc fusion protein corresponding to amino acids 22-202 of human TNFRSF11B.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes human osteoprotegerin (OPG).
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (1:1000)
    Immunoprecipitation (1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4982
  • Gene Name:
  • Gene Alias:
  • MGC29565,OCIF,OPG,TR1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 11b
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • osteoclastogenesis inhibitory factor,osteoprotegerin
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