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Last updated: 2016/10/23
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ABCC4 monoclonal antibody, clone M4I-10

  • Catalog # : MAB3400
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against recombinant ABCC4.
  • Immunogen:
  • Recombinant protein corresponding to chimeric protein with amino acids 372-431 of human ABCC4 and bacterial maltose-binding protein.
  • Host:
  • Rat
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • MRP4 transports cyclic nucleotides and anti-retroviral compounds. Anti-MRP4 clone M4I-10 reacts with human multidrug resistance protein 4 as well as with the mouse orthologue of the transporter molecule (Mrp4).
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunohistochemistry (Frozen sections) (1:20)
    Immunocytochemistry (1:20-1:50)
    Western Blot (1:20-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum-free culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Flow Cytometry
  • Gene Information
  • Gene Name:
  • ABCC4
  • Gene Alias:
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, sub-family C, member 4,OTTHUMP00000018560,bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4),canalicular multispecific organic anion transporter (ABC superfamily),multidrug resistance-associated protein 4,multispecif
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