Rat monoclonal antibody raised against recombinant ABCC4.
Recombinant protein corresponding to chimeric protein with amino acids 372-431 of human ABCC4 and bacterial maltose-binding protein.
MRP4 transports cyclic nucleotides and anti-retroviral compounds. Anti-MRP4 clone M4I-10 reacts with human multidrug resistance protein 4 as well as with the mouse orthologue of the transporter molecule (Mrp4).
Immunohistochemistry (Frozen sections) (1:20) Immunocytochemistry (1:20-1:50) Western Blot (1:20-1:50) The optimal working dilution should be determined by the end user.
In serum-free culture supernatant (0.09% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq
ATP-binding cassette, sub-family C, member 4,OTTHUMP00000018560,bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4),canalicular multispecific organic anion transporter (ABC superfamily),multidrug resistance-associated protein 4,multispecif