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Last updated: 2017/11/19
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ABCC3 monoclonal antibody, clone M3II-9

  • Catalog # : MAB3384
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ABCC3.
  • Immunogen:
  • Recombinant fusion protein corresponding to amino acids 830-949 of human ABCC3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • M3II-9 reacts with an internal epitope of human MRP-3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. Does not cross-react with human MDR1, MRP1, MRP2 or MRP-5 gene products.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunocytochemistry (1:20-1:50)
    Immunohistochemistry (Frozen sections) (1:20)
    Western Blot (1:20-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 8714
  • Gene Name:
  • ABCC3
  • Gene Alias:
  • ABC31,EST90757,MLP2,MOAT-D,MRP3,cMOAT2
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, sub-family C, member 3,canicular multispecific organic anion transporter,multidrug resistance associated protein
  • Gene Pathway
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