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Last updated: 2016/12/11
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ERCC4 monoclonal antibody, clone 219

  • Catalog # : MAB3381
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant ERCC4.
  • Immunogen:
  • Recombinant protein corresponding to human ERCC4.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes a protein of approximately 110 KDa which is identified as XPF.
  • Form:
  • Liquid
  • Isotype:
  • IgG2, kappa
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) ( 2-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of whole cell lysate from LS174T with ERCC4 monoclonal antibody, clone 219 (Cat # MAB3381).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed, paraffin embedded human tonsil stained with ERCC4 monoclonal antibody, clone 219 (Cat # MAB3381).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2072
  • Gene Name:
  • ERCC4
  • Gene Alias:
  • RAD1,XPF
  • Gene Description:
  • excision repair cross-complementing rodent repair deficiency, complementation group 4
  • Gene Summary:
  • The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6)
  • Other Designations:
  • excision-repair, complementing defective, in Chinese hamster,xeroderma pigmentosum, complementation group F
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