Staining of paraffin section of synovial tissue from a patient with Rheumatoid Arthritis. Arrows indicate vessels (20X) staining positive for TNFSF13B using TNFSF13B monoclonal antibody, clone Buffy-2 (Cat # MAB3371).
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq
ApoL related ligand TALL-1,B-cell activating factor,B-lymphocyte stimulator,OTTHUMP00000018691,TNF and ApoL-related leukocyte expressed ligand 1,TNF homolog that activates apoptosis,delta BAFF,dendritic cell-derived TNF-like molecule,tumor necrosis factor