TNFSF13 monoclonal antibody, clone Aprily-8
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot of total cell extracts from HEK 293 cells transfected with the indicated expression vector. Aprily-8 reacts specifically with human TNFSF13L.
Immunocytochemistry
Immunostaining of HEK 293 cells transfected with a human TNFSF13 expression plasmid (left panels) , or mock transfected (right panel) by Aprily-8.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant TNFSF13.
Immunogen
Recombinant protein corresponding to amino acids 93-233 of human TNFSF13.
Host
Mouse
Reactivity
Human
Specificity
Recognizes human APRIL and TWE-PRIL. Does not cross-react with mouse APRIL and TWE-PRIL.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot of total cell extracts from HEK 293 cells transfected with the indicated expression vector. Aprily-8 reacts specifically with human TNFSF13L.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunostaining of HEK 293 cells transfected with a human TNFSF13 expression plasmid (left panels) , or mock transfected (right panel) by Aprily-8.Immunoprecipitation
Flow Cytometry
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Gene Info — TNFSF13
Entrez GeneID
8741Gene Name
TNFSF13
Gene Alias
APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand
Gene Description
tumor necrosis factor (ligand) superfamily, member 13
Omim ID
604472Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Other transcripts that skip the last exon of the upstream gene (TNFSF12) and continue with the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq
Other Designations
OTTHUMP00000174780|TNF- and APOL-related leukocyte expressed ligand 2|a proliferation inducing ligand|tumor necrosis factor (ligand) superfamily member 13 transcript variant delta|tumor necrosis factor ligand superfamily member 13 epsilon|tumor necrosis f
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Interactome
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Pathway
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Disease
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