TNFSF13 monoclonal antibody, clone Sacha-2
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More Files
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Immunocytochemistry
Immunocytochemistry on a frozen section of HEK-293T cells transfected with a human TNFSF13 expression plasmid (A) or mock transfected (B).
Flow Cytometry
TNFSF13 monoclonal antibody, clone Sacha-2 (Cat # MAB3365) detects membrane-bound human TNFSF13 by FACS. HEK 293T cells (5 X 105) were mock transfected (thin line) or transfected with an expression plasmid enabling surface expression of mouse TNFSF13 (thick line).
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Specification
Product Description
Rat monoclonal antibody raised against partial recombinant TNFSF13.
Immunogen
Recombinant protein corresponding to chimeric protein with amino acids 105-250 of human TNFSF13l and amino acids 16-108 of human ACRP30 headless.
Host
Rat
Reactivity
Human, Mouse
Specificity
Recognizes human and mouse APRIL.
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunocytochemistry
Immunocytochemistry on a frozen section of HEK-293T cells transfected with a human TNFSF13 expression plasmid (A) or mock transfected (B).Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
TNFSF13 monoclonal antibody, clone Sacha-2 (Cat # MAB3365) detects membrane-bound human TNFSF13 by FACS. HEK 293T cells (5 X 105) were mock transfected (thin line) or transfected with an expression plasmid enabling surface expression of mouse TNFSF13 (thick line). -
Gene Info — TNFSF13
Entrez GeneID
8741Gene Name
TNFSF13
Gene Alias
APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand
Gene Description
tumor necrosis factor (ligand) superfamily, member 13
Omim ID
604472Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Other transcripts that skip the last exon of the upstream gene (TNFSF12) and continue with the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq
Other Designations
OTTHUMP00000174780|TNF- and APOL-related leukocyte expressed ligand 2|a proliferation inducing ligand|tumor necrosis factor (ligand) superfamily member 13 transcript variant delta|tumor necrosis factor ligand superfamily member 13 epsilon|tumor necrosis f
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