IL7 monoclonal antibody, clone BVD10-11C10
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Specification
Product Description
Rat monoclonal antibody raised against recombinant IL7.
Immunogen
Recombinant protein corresponding to human IL7.
Host
Rat
Reactivity
Human
Specificity
human Interleukin-7 (IL-7).
Form
Liquid
Isotype
IgG2a
Recommend Usage
Western Blot (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Western Blot
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Gene Info — IL7
Entrez GeneID
3574Gene Name
IL7
Gene Alias
IL-7
Gene Description
interleukin 7
Omim ID
146660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq
Other Designations
IL7 nirs variant 6
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Interactome
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Pathway
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Disease
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