IL3 monoclonal antibody, clone BVD3-1F9
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Specification
Product Description
Rat monoclonal antibody raised against recombinant IL3.
Immunogen
Recombinant protein corresponding to human IL3.
Host
Rat
Reactivity
Human
Specificity
human Interleukin-3 (IL-3).
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Immunofluorescence
Flow Cytometry
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Gene Info — IL3
Entrez GeneID
3562Gene Name
IL3
Gene Alias
IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF
Gene Description
interleukin 3 (colony-stimulating factor, multiple)
Omim ID
147740Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq
Other Designations
P-cell stimulating factor|hematopoietic growth factor|interleukin 3|mast-cell growth factor|multilineage-colony-stimulating factor
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Interactome
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Pathway
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Disease
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Publication Reference
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Structure-function relationships of interleukin-3. An analysis based on the function and binding characteristics of a series of interspecies chimera of gibbon and murine interleukin-3.
Kaushansky K, Shoemaker SG, Broudy VC, Lin NL, Matous JV, Alderman EM, Aghajanian JD, Szklut PJ, VanDyke RE, Pearce MK, et al.
The Journal of Clinical Investigation 1992 Nov; 90(5):1879.
Application:ELISA, IP, RIA, WB-Re, WB-Tr, Hamster, BHK cells, OCIM1 cells, Recombinant proteins.
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Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.
Immunological Reviews 2006 Jun; 127:5.
Application:Det Ab, ELISA IP, Human, Supernatants from cells cultured and stimulated ex vivo with different agents and biological fluids like sera/plasma, bronehoalveolar lavage, ascites, urines, cerebrospinal fluids, saliva, and sputa. .
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Structure-function relationships of interleukin-3. An analysis based on the function and binding characteristics of a series of interspecies chimera of gibbon and murine interleukin-3.
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