Bcl2 monoclonal antibody, clone 10C4
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide Bcl2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 61-76 of mouse Bcl2.
Host
Mouse
Reactivity
Mouse, Rat
Specificity
Mouse and Rat Bcl-2.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — Bcl2
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Publication Reference
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Nonionic detergents induce dimerization among members of the Bcl-2 family.
Hsu YT, Youle RJ.
The Journal of Biological Chemistry 1997 May; 272(21):13829.
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The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated.
Gottschalk AR, Boise LH, Oltvai ZN, Accavitti MA, Korsmeyer SJ, Quintans J, Thompson CB.
Cell Death Differ 1996 Jan; 3(1):113.
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Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.
Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H, Tsujimoto Y.
Nature 1995 Apr; 374(6525):811.
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Nonionic detergents induce dimerization among members of the Bcl-2 family.
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