Klrb1c monoclonal antibody, clone PK136
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More Files
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Flow Cytometry
Splenocytes from a C57BL/6 mouse were double stained with Klrb1c monoclonal antibody, clone PK136 (Cat # MAB3244)-R-phycoerythrinand rat anti-mouse CD49b/pan NK-FITC (clone DX5). Small lymphocytes were then gated and analyzed by flow cytometry.
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Specification
Product Description
Mouse monoclonal antibody raised against native Klrb1c.
Immunogen
Native Klrb1c from CE mouse spleen and bone marrow cells enriched for NK-1+ cells.
Host
Mouse
Reactivity
Mouse
Specificity
Mouse NK1.1 alloantigen, Mr 80-85 KDa (39 KDa under reducing conditions).
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Immunoprecipitation
Flow Cytometry
Splenocytes from a C57BL/6 mouse were double stained with Klrb1c monoclonal antibody, clone PK136 (Cat # MAB3244)-R-phycoerythrinand rat anti-mouse CD49b/pan NK-FITC (clone DX5). Small lymphocytes were then gated and analyzed by flow cytometry. -
Gene Info — Klrb1c
Entrez GeneID
17059Gene Name
Klrb1c
Gene Alias
AI462337, CD161, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1c
Gene Description
killer cell lectin-like receptor subfamily B member 1C
Gene Ontology
HyperlinkGene Summary
locus C|lymphocyte antigen 59|natural killer cell receptor protein NKR-P1C|natural killer cell receptor-P1|natural killer cell-associated antigen 1
Other Designations
killer cell lectin-like receptor subfamily A member 1C|lymphocyte antigen 55 complex, locus C|lymphocyte antigen 59|natural killer cell receptor protein NKR-P1C|natural killer cell receptor-P1|natural killer cell-associated antigen 1
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Publication Reference
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MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection.
Routes JM, Ryan JC, Ryan S, Nakamura M.
International Immunology 2001 Oct; 13(10):1301.
Application：Flow Cyt, Func, Mouse, Mouse nature killer cells.
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Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice.
L D Poulton, M J Smyth, C G Hawke, P Silveira, D Shepherd, O V Naidenko, D I Godfrey, A G Baxter.
International Immunology 2001 Jul; 13(7):887.
Application：Flow Cyt, Mouse, Mouse natural killer cells.
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Natural killer cell proliferation induced by anti-NK1.1 and IL-2.
Reichlin A, Yokoyama WM.
Immunology and Cell Biology 1998 Apr; 76(2):143.
Application：Flow Cyt, Func, Mouse, Mouse natural killer cells.
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MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection.
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