Product Browser

Last updated: 2017/7/16
  • Related Product Showcase
  • By Research Area
  • By Pathway
  • By Disease

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location
Vote for Cancer Research Topics & Genes to Win One Free Antibody
pathway

NFATC1 monoclonal antibody, clone AT1C3

  • Catalog # : MAB3209
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant NFATC1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 428-716 of human NFATC1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Cell lysates of Ramos (20 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with NFATC1 monoclonal antibody, clone AT1C3 (Cat # MAB3209 ; 1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4772
  • Gene Name:
  • NFATC1
  • Gene Alias:
  • MGC138448,NF-ATC,NFAT2,NFATc
  • Gene Description:
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Gene Summary:
  • The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq
  • Other Designations:
  • NFAT transcription complex cytosolic component,nuclear factor of activated T-cells, cytosolic component 1
  • RSS
  • YouTube
  • Linkedin
  • Facebook