LY96 monoclonal antibody, clone 9F1B1
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Specifications
Product Description
Mouse monoclonal antibody raised against recombinant LY96.
Immunogen
Recombinant protein corresponding to amino acids 2-160 of human LY96.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Isotype
IgG
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of (A) 25 and (B) 125 ng of LY96 recombinant protein with LY96 monoclonal antibody, clone 9F1B1 (Cat # MAB2752) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of LY96 in human spleen with LY96 monoclonal antibody, clone 9F1B1 (Cat # MAB2752) at 2.5 ug/mL . -
Gene Info — LY96
Entrez GeneID
23643Protein Accession#
NP_056179Gene Name
LY96
Gene Alias
MD-2, MD2
Gene Description
lymphocyte antigen 96
Omim ID
605243Gene Ontology
HyperlinkGene Summary
The MD-2 protein appears to associate with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. [provided by RefSeq
Other Designations
MD-2 protein|myeloid differentiation protein-2
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Pathways
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Diseases
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Publication Reference
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The Toll-IL-1 receptor adaptor family grows to five members.
O'Neill LA, Fitzgerald KA, Bowie AG.
Trends in Immunology 2003 Jun; 24(6):286.
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Toll-like receptors.
Takeda K, Kaisho T, Akira S.
Annual Review of Immunology 2001 Dec; 21:335.
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Innate immune recognition.
Janeway CA Jr, Medzhitov R.
Annual Review of Immunology 2001 Oct; 20:197.
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The Toll-IL-1 receptor adaptor family grows to five members.
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