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Last updated: 2016/12/11
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PTPRT monoclonal antibody, clone T20-AF3C7

  • Catalog # : MAB2740
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant PTPRT.
  • Immunogen:
  • Recombinant protein corresponding to human PTPRT.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:5000)
    Immunoprecipitation (2 ug)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Immunoblot analysis of cell lysates.
    Lane 1 : Bosc23 cell lysate.
    Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441 a. a.).
    Lane 3 : Bosc23 cell lysate transfected with Myc/His/PTPRT rho (887-1169 a. a.).
    Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1.
  • Immunoprecipitation
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • PTPRT
  • Gene Alias:
  • KIAA0283,RPTPrho
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, T
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031658,receptor protein tyrosine phosphatase
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