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Last updated: 2017/11/19
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PTPRN monoclonal antibody, clone AFT38

  • Catalog # : MAB2710
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant PTPRN.
  • Immunogen:
  • Recombinant protein corresponding to human PTPRN.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Immunoblot analysis of cell lysates.
    Lane 1 : Bosc23 cell lysate.
    Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441 a. a.).
    Lane 3 : Bosc23 cell lysate transfected with Myc/His/PTPRN (709-979 a. a.).
    Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5798
  • Gene Name:
  • PTPRN
  • Gene Alias:
  • FLJ16131,IA-2,IA-2/PTP,IA2,ICA512,R-PTP-N
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, N
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq
  • Other Designations:
  • islet cell antigen 2,islet cell antigen 512,islet cell autoantigen 3,protein tyrosine phosphatase-like N
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