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Last updated: 2016/10/23
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PTPN7 monoclonal antibody, clone AFPK32

  • Catalog # : MAB2708
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant PTPN7.
  • Immunogen:
  • Recombinant protein corresponding to human PTPN7.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Immunoblot analysis of cell lysates.
    Lane 1 : Bosc23 cell lysate.
    Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441 a. a.).
    Lane 3 : Bosc23 cell lysate transfected with Myc/His/PTPN7.
    Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5778
  • Gene Name:
  • PTPN7
  • Gene Alias:
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000034115,dual specificity phosphatase 1,hematopoietic protein-tyrosine phosphatase,protein-tyrosine phoshatase, nonreceptor-type, stress induced
  • Gene Pathway
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