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Last updated: 2017/3/26
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DUSP4 monoclonal antibody, clone AFPK7

  • Catalog # : MAB2704
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant DUSP4.
  • Immunogen:
  • Recombinant protein corresponding to human DUSP4.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Immunoblot analysis of cell lysates.
    Lane 1 : Bosc23 cell lysate.
    Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau.
    Lane 3 : Bosc23 cell lysate transfected with Myc/His/PK7.
    Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1846
  • Gene Name:
  • DUSP4
  • Gene Alias:
  • HVH2,MKP-2,MKP2,TYP
  • Gene Description:
  • dual specificity phosphatase 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq
  • Other Designations:
  • MAP kinase phosphatase 2,VH1 homologous phosphatase 2,serine/threonine specific protein phosphatase
  • Gene Pathway
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