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Last updated: 2021/4/11
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SPTB monoclonal antibody, clone DB2 

  • Catalog # : MAB2516
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native SPTB.
  • Immunogen:
  • Native purified human SPTB.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to the 220kD human erythroid beta-spectrin. The protein is also present in the membranes of human skeletal muscle cells. Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific to erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Monoclonal antibody to erythroid beta-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Native Purified Protein.
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 6710
  • Gene Name:
  • SPTB
  • Gene Alias:
  • HSpTB1
  • Gene Description:
  • spectrin, beta, erythrocytic
  • Other Designations:
  • beta I spectrin form betaI sigma3,beta-spectrin,membrane cytoskeletal protein,spectrin beta,spectrin, beta, erythrocytic (includes sperocytosis, clinical type I),spectrin, beta, erythrocytic (includes spherocytosis, clinical type I),spherocytosis, clinica
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