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Last updated: 2017/11/12
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ITGB3 monoclonal antibody, clone BB10

  • Catalog # : MAB2510
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGB3.
  • Immunogen:
  • Native purified human ITGB3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with b3 integrin including the GPIIIa of platelets. b3-Integrins contain receptors for vitronectin, fibrinogen, and Von Willebrands factor and, in some instances fibronectin. The b3-Integrin subunit is a common subunit protein for this integrin family. The aIIb-Integrin subunit is a specific marker for platelets and megakaryocytes and can be utilized for this purpose in various immunological techniques. Monoclonal antibodies against the b3-Integrin subunits and the aIIb-Integrin subunit can be used in immunoblotting, immunoprecipitation and immunostaining experiments. Monoclonal antibody to b3 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Native Purified Protein.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 3690
  • Gene Name:
  • ITGB3
  • Gene Alias:
  • CD61,GP3A,GPIIIa
  • Gene Description:
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • Gene Summary:
  • The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
  • Other Designations:
  • integrin beta chain, beta 3,platelet glycoprotein IIIa
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