ORC3L monoclonal antibody, clone 1D6
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Specification
Product Description
Rat monoclonal antibody raised against ORC3L.
Immunogen
Human ORC3L.
Host
Rat
Reactivity
Human
Specificity
human ORC3L.
Form
Liquid
Isotype
IgG2b
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
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Gene Info — ORC3L
Entrez GeneID
23595Gene Name
ORC3L
Gene Alias
LAT, LATHEO, ORC3
Gene Description
origin recognition complex, subunit 3-like (yeast)
Omim ID
604972Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016835|OTTHUMP00000040611|homolog of latheo, Drosophila|origin recognition complex, subunit 3
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Interactome
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Pathway
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Disease
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Publication Reference
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Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus.
Schepers A, Ritzi M, Bousset K, Kremmer E, Yates JL, Harwood J, Diffley JF, Hammerschmidt W.
The EMBO Journal 2001 Aug; 20(16):4588.
Application：ChIP, WB, Human, A39 cells.
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Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus.
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